Selected Publications
Wheeler RA, Twining RC, Jones JJ, Slater JM, Grigson PS, Carelli RM (2008) Behavioral and electrophysiological indices of negative affect predict cocaine self-administration, Neuron, 57, 774–785.
Owesson-White CA, Cheer JF, Beyene M, Carelli RM, Wightman RM (2008) Dynamic changes in accumbens dopamine linked to learning of intra-cranial self-stimulation. Proceedings of the National Academy of Sciences, 105(33):11957-62.
Roitman MF, Wheeler RA, Wightman RM, Carelli RM (2008) Real-time chemical responses in the nucleus accumbens differentiate rewarding and aversive stimuli. Nature Neuroscience, 11(12):1376-1377.
Jones JL, Day JJ, Aragona BJ, Wheeler RA, Wightman RM, Carelli RM (2009) Basolateral amygdala modulates terminal dopamine release in the nucleus accumbens and conditioned responding. Biological Psychiatry, 67(8):737-44.
Day JJ, Jones JL, Wightman RM, Carelli RM (2010) Phasic nucleus accumbens dopamine release encodes reward cost during effort-related decision making. Biological Psychiatry, 68(3):306-309. PMCID: PMC2907444.
Wheeler RA, Aragona BJ, Fuhrmann KA, Day JJ, Jones JJ, Wightman RM, Carelli RM (2011) Cocaine cues drive opposing context-dependent shifts in reward processing and emotional state, Biological Psychiatry, 69(11):1067-74. PMCID: PMC3090459.
Cacciapaglia F, Wightman RM, Carelli RM (2011) Rapid dopamine signaling differentially modulates distinct microcircuits within the nucleus accumbens during sucrose-directed behavior. The Journal of Neuroscience, 31(39):13860-9. PMCID: PMC3197228.
Sugam JA, Day JJ, Wightman RM, Carelli RM (2012) Phasic nucleus accumbens dopamine encodes risk-based decision-making behavior. Biological Psychiatry. 71(3):199-205, PMCID: PMC3253943.
Cameron CM, Carelli RM (2012) Cocaine abstinence alters nucleus accumbens cell firing dynamics during goal-directed behaviors for cocaine and sucrose. The European Journal of Neuroscience. 35(6):940-51. PMCID: PMC3674635.
Saddoris MP, Sugam JA, Cacciapaglia F, Carelli RM (2013) Rapid dopamine dynamics in the accumbens core and shell: Learning and action. Invited review, Frontiers in Bioscience, 5:273-288. PMCID: PMC3897221.
Sugam JA, Saddoris MP, Carelli RM (2014) Nucleus accumbens neurons track behavioral preferences and reward outcomes during risky decision making. Biological Psychiatry. 75(10):807-16. PMCID: PMC3992205.
Carelli RM, West EA (2014) When a good taste turns bad: Neural mechanisms underlying the emergence of negative affect and natural reward devaluation by cocaine. Invited review, Neuropharmacology, 76:360-9. PMCID: PMC4160877.
Saddoris MP, Carelli RM (2014) Cocaine self-administration abolishes associative neural encoding in the nucleus accumbens necessary for higher-order learning, Biological Psychiatry. 75:156–164. PMCID: PMC3865233.
Cerri D, Saddoris MP, Carelli RM (2014) Nucleus accumbens core neurons encode value-independent associations necessary for sensory preconditioning. Behavioral Neuroscience. 128(5):567-78. PMCID: PMC4176687.
Saddoris MP, Sugam JA, Stuber GD, Witten I, Deisseroth K, Carelli RM (2015) Mesolimbic dopamine dynamically tracks, and is causally linked to, discrete aspects of value-based decision making. Biological Psychiatry. 77(10):903-11. PMCID: PMC4416981.
Saddoris MP, Cacciapaglia F, Wightman RM, Carelli RM (2015) Differential dopamine release dynamics in the nucleus accumbens core and shell reveal complementary signals for error prediction and incentive motivation. The Journal of Neuroscience. 35(33):11572-82. PMCID: PMC4540796.
Schultz W, Carelli RM, Wightman RM (2015) Phasic dopamine signals: from subjective reward value to formal economic utility. Current Opinion in Behavioral Sciences, 5:147-154. PMCID: PMC4692271.
Saddoris M, Wang X, Sugam J, Carelli RM (2016) Cocaine self-administration experience induces pathological phasic accumbens dopamine signals and abnormal incentive behaviors in drug-abstinent rats. The Journal of Neuroscience, 36(1):235-50. PMCID: PMC4701963.
West E, Carelli RM (2016) Nucleus accumbens core and shell differentially encode reward-associated cues following reinforcer devaluation. The Journal of Neuroscience, 36(4):1128-39. Featured Article. PMCID: PMC4728721.
Owesson-White C, Belle A, Herr N, Peele J, Gowrishankar P, Carelli RM, Wightman RM (2016) Cue-evoked dopamine release rapidly modulates D2 neurons in the nucleus accumbens during motivated behavior. The Journal of Neuroscience, 36(22):6011-21. PMC – In Process.
Saddoris MP, Sugam J, Carelli RM (in press) Prior cocaine experience impairs normal phasic dopamine signals of reward value in accumbens shell. Neuropsychopharmacology.